The content of the article
- Composition and form of release Glucophage Long 500
- Functions Glucofage Long 500
- Results from taking Glucofage Long 500 for weight loss
- Indications Glucofage Long
- Contraindications
- How to take Glucofage Long 500 for weight loss
- Compatibility with other medicines
- Side effects
- Glucophage Price Long 500
In pursuit of a slim figure, some women are ready to do anything, even take drugs that are not intended for this. The main factor in using Glucofage Long 500 is type 2 diabetes, but girls use it for weight loss. This choice is due to the fact that the drug stimulates the elimination of sugar, is indicated for pathological obesity. The use of the medication for losing weight in healthy people is not recommended by doctors.
Composition and form of release Glucophage Long 500
The drug is manufactured by the French pharmaceutical company MERCK SANTE. The medication is presented in the form of oval white tablets. The active substance of the composition is metformin hydrochloride, which is 500 mg per tablet. Additional components:
- microcrystalline cellulose;
- hypromellose;
- povidone;
- carmellose sodium;
- magnesium stearate.
Functions Glucofage Long 500
The active substance metformin reduces blood sugar, which rises with food. This is a natural process with the inclusion of the pancreas. It secretes insulin, which neutralizes glucose to fat cells. The active substance metformin produces an increase in glycogen production, acts on the enzyme glycogen synthetase, increasing the transport capacity of membrane-type glucose transporters.
The drug is involved in the breakdown of sugars, correction and normalization of lipid metabolism. Functions of the tablets:
- speeds up the removal of simple sugars from food,
- normalizes the processes of metabolism and digestion;
- protects the organs of the gastrointestinal tract from toxins and toxins;
- creates ideal conditions for burning fat, removing cholesterol.
The hypoglycemic drug is taken orally, is a member of the biguanide group, and lowers plasma glucose. Since the medicine is not a stimulator of insulin secretion, hypoglycemia does not occur. Glucophage Long increases the sensitivity of receptors located on the periphery to insulin, the utilization of sugar by cells. By inhibiting the processes of gluconeogenesis and glycogenolysis, the production of glucose by the liver decreases, and its absorption in the intestine slows down.
Results from taking Glucofage Long 500 for weight loss
Patients who took Glucofage Long 500 mg diet pills noted that the drug helps to cope with extra pounds. Such effects are explained by the actions of the drug:
- Normalizes blood sugar. The drug reduces the increased concentration of glucose and remains at the same level normal.
- Accelerates the process of oxidation of fatty acids. Due to this, the digestion process improves, minerals and vitamins are more fully absorbed..
- Glucophage Long does not allow digestion of natural carbohydrates and sweets, therefore, the body does not accumulate excess empty calories and the volume of insulin does not increase. Due to this scheme, calories are not processed into fat, and the produced insulin reduces appetite and does not allow hunger to manifest itself for a long time.
- Normalizes fat (lipid) metabolism – takes control of the breakdown of carbohydrates to fat.
- It does not help to burn the already accumulated fat layer – for this you need to engage in sports and limit nutrition.
- Normalizes the pancreas.
- To obtain the desired result, it is necessary to balance the acidity of the gastric juice, to avoid overloads, because the accumulation of lactic acid negatively affects the effect of the drug.
Indications Glucofage Long
In medical practice, glucophage is used to treat diabetes. Indications for its use:
- Type 2 diabetes mellitus (not insulin-dependent), accompanied by obesity. It should be combined with physical activity and diet, other hypoglycemic drugs.
- Elevated sugar levels (maintenance monotherapy) without signs of obesity and with undiagnosed diabetes.
- Overweight without diabetes – is prescribed only by an endocrinologist or therapist in combination with a diet and the necessary level of physical activity.
Contraindications
The drug is prescribed with caution when performing heavy physical exertion, because this can lead to ketoacidosis. The use of Glucofage Long 500 for weight loss has a number of contraindications. These include:
- renal failure – due to a possible exacerbation of the disease and general intoxication;
- impaired renal function – fever, dehydration, prolonged diarrhea, poisoning, acute infections, persistent vomiting;
- heart, pulmonary insufficiency, performed operations on the heart or lungs;
- liver trauma;
- low-calorie diet containing less than 1000 kcal per day;
- pregnancy, breastfeeding (lactation);
- ketoacidosis;
- acute myocardial infarction;
- age up to 18 and over 65 years old;
- alcoholism, acute alcohol intoxication;
- individual intolerance to the components of the composition.
How to take Glucofage Long 500 for weight loss
Pills for weight loss are taken once a day, since metformin is a substance with long absorption and long-term action. The first 3-5 days, 1 tablet per day is taken. With excess weight over 20 kg and a favorable reaction to the drug, you can increase the dosage to 2 capsules (1000 mg / day). Glucophage is taken in the morning or afternoon with meals, washed down with a glass of water. The course of treatment is 3 weeks, then a break is made for 2 months.
If you take diet pills without a break, their effect is significantly reduced. After a well-tolerated initial course, it is allowed to repeat the dose in an increased dose. The maximum daily dosage will be 2000 mg of metformin in two doses with intervals between them of at least 8 hours. During treatment, you need to drink more water in order to remove the breakdown products of the drug by the kidneys without toxic effects..
A month before the planned conception, it is required to refuse to take pills. If pregnancy occurs during treatment with metformin, you should immediately consult a doctor. It is also necessary to stop taking the tablets two days before the radiograph using contrast agents based on iodide compounds. Treatment resumes two days after the procedure. A number of special instructions for the use of medication for weight loss:
- Due to the accumulation of metformin in patients, lactic acidosis (accumulation of toxic substances) can occur, which leads to death in the absence of emergency treatment. Cases of complications are more pronounced in patients with diabetes mellitus against the background of renal failure. Prolonged fasting and drinking can aggravate the condition..
- Symptoms of lactic acidosis: shortness of breath, abdominal pain, hypothermia, coma.
- You need to stop taking Metformin 2 days before surgery, and two days later, resume.
- Before you start taking, you should determine the level of serum creatinine or its clearance in order to avoid manifestations of kidney complications.
- The caution of taking Glucofage for weight loss should be observed when combined with antihypertensive drugs, diuretics, anti-inflammatory drugs of the non-steroid group. It is not recommended to take pills for bronchopulmonary infections, infectious diseases of the genitourinary tract.
- Taking the drug does not affect the ability to concentrate, think clearly, therefore, the management of transport and dangerous mechanisms is not prohibited.
Compatibility with other medicines
To reduce the possible toxic effects of Glucofage and avoid side effects, it is recommended not to combine the use of diet pills with certain medications. These include:
- drugs that reduce sugar, if their combined use is not prescribed by a doctor;
- antipsychotics, antidepressants, stimulants;
- alcohol and medicines containing it;
- loop diuretics;
- antihypertensive (pressure-lowering) drugs;
- cationic drugs secreted in the renal tubules (Digoxin, Quinine, Quinidine, Morphine);
- derivatives of sulfonylureas, acarbose, salicylates (hypoglycemia may develop).
Side effects
The risk of side effects after taking Glucofage Long 500 for weight loss remains at a high level. Possible negative effects include:
- digestive and taste disorders, metallic taste in the mouth, vomiting, nausea;
- skin rashes, ulcers, itching, erythema, allergic reactions (to exclude them, you need to start taking with the lowest possible test dose of 500 mg and then gradually increase);
- lactic acidosis;
- nervous tension;
- diarrhea, constipation, cramping in the stomach, intestines, colic, abdominal pain, digestive tract disorders;
- palpitations, heart pain, shortness of breath;
- dizziness, blind spots or circles in front of the eyes, confusion, loss of concentration, headache.
An overdose of metformin during weight loss leads to the development of lactic acidosis, which can result in death. If you exceed the dose several times, you urgently need to seek medical help. Doctors determine the level of lactate, clarify the diagnosis and conduct symptomatic therapy. The hemodialysis procedure is used to remove toxins..
Glucophage Price Long 500
Glucophage tablets can be purchased not only in a concentration of 500 mg. There are other options. Their cost depends on the concentration of metformin, the number of tablets in the package, the level of the trade margin. Approximate prices for medicine for weight loss in Moscow and St. Petersburg will be:
Type of pills | Internet cost, rubles | Pharmacy price tag, rubles |
500 mg 30 pcs. | 273 | 290 |
500 mg 60 pcs. | 407 | 412.3 |
750 mg 30 pcs. | 326 | 350 |
750 mg 60 pcs. | 504 | 524 |
1000 mg 60 pcs. | 687 | 699 |
Could you please provide me with detailed information about Glucophage Long 500? I’m particularly interested in knowing its instructions for use, composition, release form, and current price. Additionally, I would like to understand if this medication is recommended specifically for weight loss or if it has additional benefits. Thank you in advance for your help!